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Évolution de la virulence de V. crassostreae en lien avec l’huître en tant qu’hôte et les phages en tant que prédateurs ArchiMer
Piel, Damien.
Understanding the ecological and evolutionary dynamics of infectious agents is important for diagnosing, predicting and preventing diseases in farmed and wild species. This project was aimed at studying the evolution of V. crassostreae virulence in relation to the oyster as a host and to the phages as predators. We identified the molecular mechanisms leading to the adaptation of vibrios to oysters. We demonstrated the emergence of virulent strains of V. crassostreae in the area impacted by the juvenile oyster mortality syndrome. The emergence of more virulent V. crassostreae strains is linked to the acquisition of a plasmid encoding a type 6 secretion system responsible for lethal activity towards oyster hemocytes. This project also provides knowledge on...
Tipo: Text Palavras-chave: Vibrio; Interactions hôte/parasite; Emergence de pathogènes; Bactériophages; V. crassostreae; Mécanismes moléculaires; Vibrio; Host/parasite interactions; Pathogen emergence; Bacteriophages.
Ano: 2019 URL: https://archimer.ifremer.fr/doc/00690/80203/83289.pdf
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